Kev Txhim Kho thiab Qhov Zoo ntawm Qhuav Granulation (Cov Menyuam Compactor) Tshuab
Qhuav granulation yog txheej txheem granulation tshiab tsim tom qab tsoos qhuav granulation. Tib neeg tseem hu nws Cov Menyuam Compactor, lossis cov menyuam siv tshuab thev naus laus zis. Nws yog txheej txheem granulation uas siv cov dej ua kua ntawm cov khoom siv nws tus kheej kom ncaj ncaj, tsim, zuaj, thiab ua kom cov hmoov nyoos hmoov dhau los ntawm kev txau ntawm qhuav granulator xovxwm rau cov menyuam.
Cov yam ntxwv ntawm cov hmoov qhuav qhuav: cov hmoov nyoos hmoov tau tsim ncaj qha thiab ua kom tsis tu ncua, thiab cov txheej txheem ua kom qhuav thiab ua kom qhuav raug tso tseg, thiab ntau qhov hluav taws xob hluav taws xob tau txais kev cawmdim: cov txheej txheem ua kom zoo ib puag ncig tsis tas yuav ntxiv cov ntawv txhuam, uas yog kev lag luam thiab tsis muaj kuab paug. Qhuav granulator, Cov Menyuam Compactor yog lub zog txuag hluav taws xob thiab cov khoom siv ib puag ncig zoo nrog kev nqis peev qis, ua haujlwm tau zoo thiab txuag neeg ua haujlwm, khoom siv thiab peev nyiaj txiag. Cov Menyuam Compactor yog lub cim tom ntej zoo tshaj plaws rau txheej txheem Granulation.
Txheej txheem cej luam ntawm Qhuav Granulator(Cov Menyuam Compactor)
Kev lag luam kws lag luam cuam tshuam nrog kev ua haujlwm ntawm ntau yam khoom xyaw kws tshuaj (APIs) thiab ib lossis ntau yam khoom siv. Feem ntau ntawm cov ntaub ntawv raw yog hmoov zoo, thiab cov hmoov no muaj qhov sib txawv me me, qhov sib npaug tsis sib xws, thiab cov dej tsis zoo. Yooj yim rau cov duab. Yog li ntawd, txheej txheem txheej txheem granulation tseem ceeb yuav tsum tau ua ua ntej theem tom ntej ntawm cov ntsiav tshuaj nrawm, ntim tshuaj ntsiav, lossis ntim ncaj qha ntawm cov khoom siv raw hauv daim ntawv. Tam sim no, muaj tsuas yog 4 hom txheej txheem granulation:
1. Tsoos ntub dej granulation:
a Z Hom Los Ntawm Tov Khoom --- Swaying Granulator (Oscillating Granulator)
Ntawd yog, los ntawm kev tov ua ntej sib tov rau hauv ntub&"cov khoom muag &"; Tam sim no, txoj kev no tseem siv los ntawm qee cov tuam ntxhab, tab sis hom khoom siv no muaj teeb meem xws li kev sib xyaw tsis sib xws, tu tsis huv, kaw tsis zoo, thiab roj tuaj.
b. Ntub Dej Txoj Kev Ceev Sib xyaw Granulator
Qhov no yog thev naus laus zis nrov tshaj plaws niaj hnub no rau kev ua granulation, tshwj xeeb tshaj yog rau cov ntsiav tshuaj thiab tshuaj ntsiav. Tib neeg hu nws RMG lossis siab sib tov sib xyaw Ncuav cov hmoov qhuav rau hauv cov khoom sib xyaw thiab tshuab txau rau sab hauv rau txheej txheem granulation. Qhov tsis yooj yim siv lub tshuab no yog txheej txheem no yuav tsum tau txheej txheem kom qhuav tom qab granulation. Txawm tias thaum lub sij hawm granulation, nws xav tau cov tshuaj hnyav hnyav.
2. Dej Txias Granulation (FBG):
Cov txheej txheem no yog kev siv tshuaj txau tshuab thiab thev naus laus zis thev naus laus zis, yog li kev sib xyaw ib txwm, ua kom qhuav, thiab txheej txheem kom qhuav tuaj yeem ua tiav hauv tib lub thawv ntim cua ib zaug. Ib yam li ntawd, nws cov cuab yeej siv thiab txheej txheem yuav tsum tau siv cov nplaum ntau, kho cov dej phwj tuaj tom qab ntxuav tas, thiab lub sij hawm granulation ntev heev. Cov txheej txheem kua txaj Granulation xav tau kev siv hluav taws xob ntau dua thiab qhov no yog cov khoom sib xyaw ua ke uas yuav ua rau muaj kev pheej hmoo ntawm Txawv Granulation cov khoom sib txawv ua tau zoo.
3. Qhuav granulation (Cov Menyuam Compactor):
Kev siv tshuab qhuav granulator tuaj yeem ua tiav los ntawm cov menyuam tiaj tus nias granulator. Suav tshuaj rho tawm nrog qee qhov txheeb ze sib xws yog tshuaj tsuag kom qhuav kom tau txais cov hmoov qhuav qhuav. Tom qab ntxiv qee cov ntaub ntawv pabcuam, nws raug nias rau hauv nyias nyias los ntawm cov zom ziab qhuav, thiab tom qab ntawd tsoo rau hauv cov granules. Qhuav granulator Txoj kev no yuav tsum muaj cov ntaub ntawv pabcuam tsawg dua, uas muaj txiaj ntsig zoo los txhim kho kev ruaj ntseg, tsis tawg thiab tawg ntawm cov granules. Feem ntau, ntxiv 0.5-1 zaug ntawm cov khoom pabcuam kom qhuav cov hmoov qhuav. Txawm li cas los xij, nws yuav tsum tau muab sau tseg tias cov tshuaj ziab qhuav uas tau los ntawm cov tshuaj tsuag kom qhuav yog hygroscopic heev. Yog li ntawd, tus yuam sij rau kev siv txoj hauv kev no yog txhawm rau nrhiav cov khoom siv tsim nyog, uas yuav tsum muaj qee qib ntawm cov nplaum thiab tsis yooj yim nqus cov dej noo, xws li lactose, pregelatinized starch, mannitol, dej-soluble acrylic resin thiab cellulose derivatives Tos.
Lub hom phiaj ntawm qhuav granulation lag luam ntawm qhuav granulator
1. Ua cov khoom siv rau hauv tus qauv zoo thiab zoo;
2. Txhawm rau kom ntsuas kom raug, xa tawm thiab tswj hwm;
3. Txo ya ya cov pa phem ua hmoov;
4. Ua kom muaj kev sib cais tsis pub sib xyaw ntawm ntau hom kab ke;
5. Txhim kho cov khoom zoo nkauj;
6. Tiv thaiv kev sib sau ua ke thaum tsim khoom ntawm qee yam khoom ruaj khov;
7. Txhim kho cov yam ntxwv ntws ntawm cov khoom sib cais;
8. Ua kom qhov ntim thiab qhov hnyav ntawm cov hmoov, uas yooj yim rau kev khaws thiab thauj mus los;
9. Txo kev phom sij hauv kev tuav cov tshuaj lom thiab corrosive;
10. Tswj tus nqi sib tov ntawm cov khoom;
11. Kho qhov porosity thiab thaj chaw tshwj xeeb ntawm cov khoom tiav;
12. Txhim kho cov cua sov hloov pauv thiab pab kev sib txuas;
13. Hloov kho cov txheej txheem lom neeg sib txawv.